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the many benefits of cbd

& other cannabinoids

Cannabidiol (CBD) is one of the many active cannabinoids in industrial grown hemp. Cannabinoids directly interact with your body's endocannabinoid system to maintain an internal balance known as homeostasis. We also have an article on how our body interacts with CBD that you can read more on how CBD affects your body.

According to Jillian Kubala, MS, RD, of Healthline.com, CBD can relieve pain, reduce anxiety and depression, alleviate cancer-related symptoms, might have neuroprotective properties, benefit heart health, and much more! Each of the 100+ cannabinoids found in hemp or even the cannabis plant serves its own purpose. For example, CBN can significantly prolong sleeping time resulting in better sleep. Therefore, CBN is the perfect for combating sleep issues such as insomnia.

CBD oil benefits list

Use the interactive CBD benefits list below to see how CBD and other cannabinoids help nurture the human brain and body. Each circle color represents a different active cannabinoid. Simply click on the cannabinoid below to learn more. We also linked published studies related to each of the cannabinoid below.

Pain & Sleep
    • "CBC reduced pain by interacting with several target proteins involved with pain reduction control." [4]
    • "CBN helps with pain and promotes vasorelaxation which is the reduction of vascular tension." [1]
    • "CBD has analgesic effects by promoting signaling of the adenosine receptor A2A by inhibiting the adenosine transporter." [13]
    • "Cannabidiol (CBD) may represent a novel class of therapeutic agents for the treatment of chronic pain by targeting α3 glycine receptors." [14]
    • "Cannabinoids including the cannabidiol (CBD) / THC buccal spray are effective in treating neuropathic pain in multiple sclerosis-related pain." [15]
    • "THC and CBD have been administered as an oral mucosal spray to 58 patients with rheumatoid arthritis. Treated patients had significant reduction in pain compared to patients given placebo." [16]
    • "CBC helped fight inflammation as much as phenylbutazone (pbz) but without the negative side effects." [5]
    • "CBC has been shown to help reduce inflammation-induced hypermotility." [6]
    • "CBG was effective in decreasing the inflammation of Inflammatory Bowel Disease (IBD) in mice." [8]
    • "Cannabidiol and O-1602 showed anti-inflammatory effects in mice with AP and improved the expression of GPR55 in the pancreatic tissue as well." [17]
    • "CBD appears to exert anti-inflammatory activity by suppressing fatty acid activity, thereby increasing concentrations of the anti-inflammatory endocannabinoid anandamide." [18]
    • "Moreover, CBD reduced acute inflammation in a murine model of collagen-induced arthritis." [19]
    • "CBN can significantly prolong sleeping time resulting in better sleep." [2]
  • Anti-Sleep Apnea
Disease Specific
    • "Cannabidiol lowers incidence of diabetes in non-obese diabetic mice." [20]
    • "The function of CBD as an antioxidant to block oxidative stress represents a novel therapeutic approach to the treatment of ophthalmic complications associated with diabetes." [21]
  • Anti-Psoratic
    • "GW Pharmaceuticals is testing the bone healing effects of CBG. They also hold a patent for the therapeutic use of CBG as a treatment for osteoporosis." [10]
    • "CBC inhibited the cell growth in tumors and cancer cells." [7]
    • "CBG was shown to inhibit the growth of colorectal cancer cells which slowed colon cancer growth." [9]
    • "CBD induced breast cancer cell death and strengthens the idea that CBD can be considered as an alternative agent for breast cancer therapy." [22]
  • Immunosuppressive
  • Anti-Ischemic
  • Vasconstriction
  • Vasorelaxant
  • Allograft Stimulant
  • Glaucoma Relief
Eating & Digestion
  • Digestive Aid
    • "CBD was shown to be effective in suppressing vomiting in the S. murinus induced by either nicotine, LiCl or cisplatin." [23]
    • "CBD produced its anti-emetic/anti-nausea effects by indirect activation of the 5-HT(1A) autoreceptors in the DRN." [24]
    • "CBG doubled food intake in rats and increased number of meals consumed. This can lead to CBG being used as a therapeutic option for cachexia, the severe weight loss stage of cancer." [11]
    • "CBG doubled food intake in rats and increased number of meals consumed. This can lead to CBG being used as a therapeutic option for cachexia, the severe weight loss stage of cancer." [11]
  • Appetite Suppressant
    • "Cannabidiol (CBD), cannabinol (CBN), and cannabigerol (CBG) has effectively treated bacteria infections such as MRSA, which is resistant to antibiotics." [3]
  • Antimicrobial
  • Antioxidant
Neurological
    • "CBD induces antidepressant-like effects comparable to those of imipramine. These effects of CBD were probably mediated by activation of 5-HT(1A) receptors." [25]
    • "CBD exhibited an anti-anxiety and antidepressant effects in animal models." [26]
    • "CBD could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling through a 5-HT1A receptor-dependent mechanism." [27]
    • "Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic [anti-anxiety] properties." [12]
    • "Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients." [28]
    • "CBD reduces anxiety in generalized social anxiety disorder (SAD) and that this is related to its effects on activity in limbic and paralimbic brain areas." [29]
  • Anti-Psychotic
  • Anti-Spasmodic
    • "Seven out of the eight epileptics receiving cannabidiol had improvement of their disease state, whereas only one placebo patient improved." [30]
    • "CBD acts, potentially in a CB(1) receptor-independent manner, to inhibit epileptiform activity in vitro and seizure severity in vivo." [31]
    • "In one study, 53 children with refractory epilepsy were given medicinal cannabis in September 2016. Parents of children reported a decrease in convulsions when cannabidiol was used in 81.3% of the cases." [32]
    • "CBD also has positive effects on attenuating psychotic-, anxiety- and depressive-like behaviors. Moreover, CBD affects synaptic plasticity and facilitates neurogenesis" [33]
    • "CBD should be considered as a potential molecule with memory-rescuing and neuroprotective properties to be used in the treatment of cognitive deficits observed in neurodegenerative disorders." [34]

featured benefits articles

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Benefits of CBD Oil for Diabetes

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Benefits of CBD Oil for Diabetes

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References

  1. "CBN helps with pain and promotes vasorelaxation which is the reduction of vascular tension." http://www.jneurosci.org/content/22/11/4720.full
  2. "CBN can significantly prolong sleeping time resulting in better sleep." https://www.ncbi.nlm.nih.gov/pubmed/7728937
  3. "Cannabidiol(CBD), cannabinol(CBN), and cannabigerol(CBG) has effectively treated bacteria infections such as MRSA, which is resistant to antibiotics." https://www.ncbi.nlm.nih.gov/pubmed/18681481
  4. "CBC reduced pain by interacting with several target proteins involved with pain reduction control." https://www.ncbi.nlm.nih.gov/pubmed/20942863
  5. "CBC helped fight inflammation as much as phenylbutazone (pbz) but without the negative side effects." https://www.sciencedirect.com/science/article/abs/pii/0024320580906311
  6. "CBC has been shown to help reduce inflammation-induced hypermotility." https://www.ncbi.nlm.nih.gov/pubmed/22300105
  7. "CBC inhibited the cell growth in tumors and cancer cells." https://onlinelibrary.wiley.com/doi/abs/10.1111/jphp.12082
  8. "CBG was effective in decreasing the inflammation of Inflammatory Bowel Disease (IBD) in mice." https://www.ncbi.nlm.nih.gov/pubmed/23415610
  9. "CBG was shown to inhibit the growth of colorectal cancer cells which slowed colon cancer growth." https://www.ncbi.nlm.nih.gov/pubmed/25269802
  10. "GW Pharmaceuticals is testing the bone healing effects of CBG. They also hold a patent for the therapeutic use of CBG as a treatment for osteoporosis." https://patents.google.com/patent/US20100292345A1/en
  11. "CBG doubled food intake in rats and increased number of meals consumed. This can lead to CBG being used as a therapeutic option for cachexia, the severe weight loss stage of cancer." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021742
  12. "Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic [anti-anxiety] properties." Journal of Psychopharmacology - Sage Publications
  13. "CBD has analgesic effects by promoting signaling of the adenosine receptor A2A by inhibiting the adenosine transporter." https://www.ncbi.nlm.nih.gov/pubmed/18728714
  14. "Cannabidiol (CBD) may represent a novel class of therapeutic agents for the treatment of chronic pain by targeting α3 glycine receptors." https://www.ncbi.nlm.nih.gov/pubmed/22585736
  15. "Cannabinoids including the cannabidiol (CBD) / THC buccal spray are effective in treating neuropathic pain in multiple sclerosis-related pain." https://www.ncbi.nlm.nih.gov/pubmed/17257464
  16. "THC and CBD have been administered as an oral mucosal spray to 58 patients with rheumatoid arthritis. Treated patients had significant reduction in pain compared to patients given placebo." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/
  17. "Cannabidiol and O-1602 showed anti-inflammatory effects in mice with AP and improved the expression of GPR55 in the pancreatic tissue as well." https://insights.ovid.com/pubmed?pmid=22850623
  18. "CBD appears to exert anti-inflammatory activity by suppressing fatty acid activity, thereby increasing concentrations of the anti-inflammatory endocannabinoid anandamide." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664885/
  19. "Moreover, CBD reduced acute inflammation in a murine model of collagen-induced arthritis." https://www.fasebj.org/doi/full/10.1096/fj.201600646R?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed
  20. "Cannabidiol lowers incidence of diabetes in non-obese diabetic mice." https://www.ncbi.nlm.nih.gov/pubmed/16698671
  21. "The function of CBD as an antioxidant to block oxidative stress represents a novel therapeutic approach to the treatment of ophthalmic complications associated with diabetes." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083879/
  22. "CBD induced breast cancer cell death and strengthens the idea that CBD can be considered as an alternative agent for breast cancer therapy." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579246/
  23. "CBD was shown to be effective in suppressing vomiting in the S. murinus induced by either nicotine, LiCl or cisplatin." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165951/
  24. "CBD produced its anti-emetic/anti-nausea effects by indirect activation of the 5-HT(1A) autoreceptors in the DRN." https://www.ncbi.nlm.nih.gov/pubmed/21827451
  25. "CBD induces antidepressant-like effects comparable to those of imipramine. These effects of CBD were probably mediated by activation of 5-HT(1A) receptors." https://www.ncbi.nlm.nih.gov/pubmed/20002102
  26. "CBD exhibited an anti-anxiety and antidepressant effects in animal models" https://www.ncbi.nlm.nih.gov/pubmed/24923339
  27. "CBD could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate cortical signalling through a 5-HT1A receptor-dependent mechanism." https://www.sciencedirect.com/science/article/pii/S0028390815302136?via%3Dihub
  28. "Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079847/
  29. "CBD reduces anxiety in generalized social anxiety disorder (SAD) and that this is related to its effects on activity in limbic and paralimbic brain areas." https://www.ncbi.nlm.nih.gov/pubmed/20829306
  30. "Seven out of the eight epileptics receiving cannabidiol had improvement of their disease state, whereas only one placebo patient improved." https://www.ncbi.nlm.nih.gov/pubmed/7028792
  31. "CBD acts, potentially in a CB(1) receptor-independent manner, to inhibit epileptiform activity in vitro and seizure severity in vivo." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819831/
  32. "In one study, 53 children with refractory epilepsy were given medicinal cannabis in September 2016. Parents of children reported a decrease in convulsions when cannabidiol was used in 81.3% of the cases." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368357/
  33. "CBD also has positive effects on attenuating psychotic-, anxiety- and depressive-like behaviors. Moreover, CBD affects synaptic plasticity and facilitates neurogenesis." https://www.sciencedirect.com/science/article/abs/pii/S1043661816000396?via%3Dihub
  34. "CBD should be considered as a potential molecule with memory-rescuing and neuroprotective properties to be used in the treatment of cognitive deficits observed in neurodegenerative disorders." https://link.springer.com/article/10.1007%2Fs12035-013-8514-7